OK. From what I remember, while the trains are fast and efficient in Europe, it is very difficult to navigate them with baggage, especially if there are numerous changes.
At Bayreuth, I will need dress clothing so will most likely require more than one bag. My next stop would be St Moritz, which involves four(!) changes on the journey.
I’m thinking rail is not the best way to navigate this journey. Even Frankfurt or other major city might be difficult but on a direct train manageable.